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ReLiver

 

Derived from an unlimited stem cell source, our cell therapy platform will ultimately transform the treatment of liver disease. We are initially targeting acute and acute-on-chronic liver failure, the most challenging conditions that currently rely on liver transplantation as the only line of treatment.

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ReLiver™ has been designed to be:

  • Used as an allogeneic cell therapy

  • Implantable via minimally invasive surgery

  • Fully functional upon implantation

  • Easily removed without sequelae once the patient’s liver regenerates

  • Does not require immunosuppression

  • Can be cryopreserved for on-demand use

Pre-clinical data supports that ReLiver® :

  • Maintains metabolic function for 12 weeks

  • Restores liver function in models of acute liver failure, improving survival and treating hepatic encephalopathy

  • Is safe: cells are contained within the implant

  • Effectively evades the host immune system